Keystone Nano Tests Promising New Cancer Treatments

Keystone Nano, a State College-based biopharmaceutical company, is developing new treatments in the fight against cancer and its new, potentially ground-breaking therapies could be available sooner rather than later.

The company is currently developing three different approaches to cancer therapy with products that address liver cancer, leukemia, and breast cancer.

Voxello: Giving a Voice to Hospitalized Patients

Venture Connection: Participant SpotlightIn the U.S. alone, there are 3.9 million hospitalized patients who can’t communicate their needs to nurses. Without proper means of communication, these patients are three times more likely to experience preventable complications, such as adverse reactions to medicine.

Voxello, led by CEO Rives Bird, has created an innovative solution. Bird brings more than 20 years of experience as an executive in multiple medical device companies, and has launched multiple successful entrepreneurial ventures in Iowa.

INDIGO Biosciences Reduces the Time and Cost of Drug Discovery

Venture Connection: Participant SpotlightINDIGO Biosciences, Inc., founded in 2005 in State College by Dr. Jack Vanden Heuvel and Dr. Blake Peterson, is a biosciences company focused on nuclear receptors, which make up a major class of therapeutic drug targets. The company has the largest global portfolio of nuclear receptor (NR) assay kits and related screening services.

INDIGO Biosciences’ original focus was to provide custom services for the screening of small molecule compounds against functional human and non-human nuclear receptors.

Over the years, the company has demonstrated success in providing quality screening services to clients within the pharmaceutical, biotechnology, food, agriculture, and nutriceutical industries, government research agencies, as well as to academic researchers.

Neutun Labs Develops Wearable App to Track Epilepsy

According to the Center for Disease Control and Prevention, more than 2.9 million adults and children in the United States suffer from active epilepsy.

Taking your medications, getting plenty of rest, and keeping your stress low are all ways to help manage epilepsy. But until now, there hasn’t been a centralized way of tracking all of these factors.

Actuated Medical Creates Products to Improve Patient Outcomes

Venture Connection: Participant SpotlightActuated Medical is a company that develops patented medical devices and is led by President and CEO Maureen L. Mulvihill, Ph.D. The idea for Mulvihill’s business came in 2006, when she was talking to a doctor who said, “I have a clinical need. I have 6 hours to get to a blood clot or my patient will have irreparable brain damage. I need a solution.” Mulvihill saw a market need for an agile small business that had actuation (electronically controlled motion) expertise. Actuated Medical, Inc. (AMI) was born with a mission to integrate motion into medical devices to improve patient outcomes and reduce healthcare costs.